The sensitizer 2,4-dinitrofluorobenzene activates caspase-3 and induces cell death in a skin dendritic cell line

In this work, a dendritic cell line derived from mouse skin (FSDC) was used, as an in vitro experimental model, to evaluate the cytotoxic effect of two chemical sensitizers, a strong sensitizer (2,4-dinitrofluorobenzene, DNFB) and a weak sensitizer (2,4-dichloronitrobenzene, DCNB). The results indic...

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Bibliographic Details
Main Author: Cruz, MT (author)
Other Authors: Duarte, CB (author), Gonçalo, Margarida (author), Figueiredo, A (author), Carvalho, AP (author), Lopes, MC (author)
Format: article
Language:eng
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10400.4/763
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/763