Absence of the spindle assembly checkpoint restores mitotic fidelity upon loss of sister chromatid cohesion

The fidelity of mitosis depends on cohesive forces that keep sister chromatids together. This is mediated by cohesin that embraces sister chromatid fibers from the time of their replication until the subsequent mitosis [1-3]. Cleavage of cohesin marks anaphase onset, where single chromatids are drag...

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Bibliographic Details
Main Author: Silva, Rui (author)
Other Authors: Mirkovic, Mihailo (author), Guilgur, Leonardo G. (author), Rathore, Om (author), Martinho, Rui Goncalo (author), Oliveira, Raquel A. (author)
Format: article
Language:eng
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10400.1/11896
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11896