Absence of the spindle assembly checkpoint restores mitotic fidelity upon loss of sister chromatid cohesion

The fidelity of mitosis depends on cohesive forces that keep sister chromatids together. This is mediated by cohesin that embraces sister chromatid fibers from the time of their replication until the subsequent mitosis [1-3]. Cleavage of cohesin marks anaphase onset, where single chromatids are drag...

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Detalhes bibliográficos
Autor principal: Silva, Rui (author)
Outros Autores: Mirkovic, Mihailo (author), Guilgur, Leonardo G. (author), Rathore, Om (author), Martinho, Rui Goncalo (author), Oliveira, Raquel A. (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Texto completo:http://hdl.handle.net/10400.1/11896
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11896