Regulation of IRES-mediated translation in p53

The tumor microenvironment is characterized by several stresses impairing canonical translation. However, specific mRNAs harbouring internal ribosome entry sites (IRES), such as several tumour suppressors and oncogenes, can overcome this impairment. The tumor suppressor TP53 gene, an important trans...

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Bibliographic Details
Main Author: Fonseca Costa, Inês (author)
Other Authors: Lacerda, Rafaela (author), López-Iniesta, M. (author), Romão, Luísa (author), Candeias, Marco M. (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Tumor
Cancer
IRES-mediated Translation
p53
Genómica Funcional e Estrutural
Online Access:http://hdl.handle.net/10400.18/7455
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7455

Internet

http://hdl.handle.net/10400.18/7455

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