Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3

Global cerebral ischemia induces selective acute neuronal injury of the CA1 region of the hippocampus. The type of cell death that ensues may include different programmed cell death mechanisms namely apoptosis and necroptosis, a recently described type of programmed necrosis. We investigated whether...

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Detalhes bibliográficos
Autor principal: Vieira, M. (author)
Outros Autores: Fernandes, J. (author), Carreto, L. (author), Anuncibay-Soto, B. (author), Santos, M. (author), Han, J. (author), Fernández-López, A. (author), Duarte, C. B. (author), Carvalho, A. L. (author), Santos, A. E. (author)
Formato: article
Idioma:eng
Publicado em: 1000
Assuntos:
Cerebral ischemia
Necroptosis
Necrostatin-1
Oxygen-glucose deprivation
Receptor-interacting Protein Kinase 3
Texto completo:http://hdl.handle.net/10773/23292
País:Portugal
Oai:oai:ria.ua.pt:10773/23292

Texto Completo

http://hdl.handle.net/10773/23292

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