Osteogenic differentiation of mesenchymal stem cells using PAMAM dendrimers as gene delivery vectors

This paper reports the use of different generations of polyamidoamine (PAMAM) dendrimers for the in vitro transfection of mesenchymal stem cells (MSCs). A systematic study was carried out on the transfection efficiency achieved by the PAMAM dendrimers using a beta-galactosidase reporter gene system....

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Bibliographic Details
Main Author: Santos, José Luís (author)
Other Authors: Oramas, Elena (author), Pêgo, Ana Paula (author), Granja, Pedro Lopes (author), Tomás, Helena (author)
Format: article
Language:eng
Published: 2019
Subjects:
PAMAM dendrimers
Bone regeneration
Nonviral gene delivery
Mesenchymal stem cells
Bone morphogenetic protein
.
Faculdade de Ciências Exatas e da Engenharia
Online Access:http://hdl.handle.net/10400.13/2464
Country:Portugal
Oai:oai:digituma.uma.pt:10400.13/2464

Internet

http://hdl.handle.net/10400.13/2464

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