Recycling antimalarial leads for cancer: Antiproliferative properties of N-cinnamoyl chloroquine analogues

Cinnamic acids and quinolines are known as useful scaffolds in the discovery of antitumor agents. Therefore, N-cinnamoylated analogues of chloroquine, recently reported as potent dual-action antimalarials, were evaluated against three different cancer cell lines: MKN-28, Caco-2, and MCF-7. All compo...

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Bibliographic Details
Main Author: Perez, Bianca C. (author)
Other Authors: Fernandes, Iva (author), Mateus, Nuno (author), Teixeira, Catia (author), Gomes, Paula (author)
Format: article
Language:eng
Published: 1000
Subjects:
HALF-MUSTARD DERIVATIVES
PHENYL NITROGEN-MUSTARD
AGENTS
ACID
DRUG
DISTAMYCIN
EXPRESSION
INHIBITORS
GROWTH
CELLS
Online Access:http://hdl.handle.net/10773/19966
Country:Portugal
Oai:oai:ria.ua.pt:10773/19966

Internet

http://hdl.handle.net/10773/19966

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