Ribonucleases and nonsense-mediated decay (NMD): An unexpected role for DIS3L2 over human NMD targets

Background: The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs carrying a premature translation-termination codon but also regulates the abundance of a large number of physiological RNAs that encode full-length proteins. In human cells, NMD-targeted mRNAs are degraded by endon...

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Bibliographic Details
Main Author: da Costa, Paulo J. (author)
Other Authors: Saramago, Margarida (author), Viegas, Sandra C. (author), Arraiano, Cecília M. (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2018
Subjects:
Nonsense-mediated mRNA Decay
NMD
Genómica Funcional e Estrutural
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/6012
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6012

Internet

http://hdl.handle.net/10400.18/6012

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