The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments

The spindle assembly checkpoint monitors the status of kinetochore-microtubule (K-MT) attachments and delays anaphase onset until full metaphase alignment is achieved. Recently, the role of spindle assembly checkpoint proteins was expanded with the discovery that BubR1 and Bub1 are implicated in the...

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Bibliographic Details
Main Author: Logarinho, Elsa (author)
Other Authors: Resende, Tatiana Pinho (author), Torres, Cláudia (author), Bousbaa, Hassan (author)
Format: article
Language:eng
Published: 2008
Subjects:
Base Sequence
Cell Cycle
Cell Cycle Proteins
Chromosomal Proteins, Non-Histone
Chromosome Pairing
HeLa Cells
Humans
Kinetochores
Microtubules
Poly-ADP-Ribose Binding Proteins
Protein-Serine-Threonine Kinases
RNA Interference
RNA, Small Interfering
Spindle Apparatus
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/61476
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/61476

Internet

http://hdl.handle.net/1822/61476

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