Delivering a disease-modifying treatment for Huntington’s disease

Huntington's disease (HD) is an incurable genetic neurodegenerative disorder that leads to motor and cognitive decline. It is caused by an expanded polyglutamine tract within the Huntingtin (HTT) gene, which translates into a toxic mutant HTT protein. Although no cure has yet been discovered, n...

Full description

Bibliographic Details
Main Author: Godinho, Bruno M. C. (author)
Other Authors: Malhotra, Meenakshi (author), O’Driscoll, Caitriona M. (author), Cryan, John F. (author)
Format: article
Language:eng
Published: 2014
Subjects:
Huntington's disease
Neurodegenerative disorder
Huntingtin gene
RNA interference
DNA enzymes
Online Access:http://hdl.handle.net/10400.21/3848
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/3848

Internet

http://hdl.handle.net/10400.21/3848

Similar Items