miR-181a negatively regulates human γδ T cell differentiation into anti-tumor effectors

Cytotoxicity and IFN-γ production by human γδ T cells underlie their potent anti-tumor functions. importantly, we have previously shown that ex vivo-isolated γδ thymocytes produced negligible IFN-γ and lacked cytolytic activity against leukemia cells but could acquire those properties upon stimulati...

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Bibliographic Details
Main Author: Gordino, Gisela (author)
Other Authors: Pereira, Sara (author), Gomes, Anita Q. (author), silva-Santos, Bruno (author), Ribot, Julie (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Immune system
miR-181a
Cancer immunotherapy
T cell differentiation
Online Access:http://hdl.handle.net/10400.21/11308
Country:Portugal
Oai:oai:repositorio.ipl.pt:10400.21/11308

Internet

http://hdl.handle.net/10400.21/11308

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