Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling

Hydrogen peroxide (H2O2) is a key signaling agent. Its best characterized signaling actions in mammalian cells involve the early oxidation of thiols in cytoplasmic phosphatases, kinases and transcription factors. However, these redox targets are orders of magnitude less H2O2-reactive and abundant th...

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Bibliographic Details
Main Author: Travasso, Rui D. M. (author)
Other Authors: Sampaio dos Aidos, Fernando (author), Bayani, Anahita (author), Abranches, Pedro (author), Salvador, Armindo (author)
Format: article
Language:eng
Published: 2017
Subjects:
Redox signaling
Redox relays
Hydrogen peroxide
Peroxiredoxins
Quantitative redox biology
Mathematical model
Online Access:http://hdl.handle.net/10316/46636
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/46636

Internet

http://hdl.handle.net/10316/46636

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