Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling

Hydrogen peroxide (H2O2) is a key signaling agent. Its best characterized signaling actions in mammalian cells involve the early oxidation of thiols in cytoplasmic phosphatases, kinases and transcription factors. However, these redox targets are orders of magnitude less H2O2-reactive and abundant th...

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Detalhes bibliográficos
Autor principal: Travasso, Rui D. M. (author)
Outros Autores: Sampaio dos Aidos, Fernando (author), Bayani, Anahita (author), Abranches, Pedro (author), Salvador, Armindo (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
Redox signaling
Redox relays
Hydrogen peroxide
Peroxiredoxins
Quantitative redox biology
Mathematical model
Texto completo:http://hdl.handle.net/10316/46636
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/46636

Texto Completo

http://hdl.handle.net/10316/46636

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