Urinary cysteinyl leukotrienes as biomarkers of endothelial activation, inflammation and oxidative stress and their relationship with organ dysfunction in human septic shock
Background: Vascular leakage due to endothelial damage is a hallmark of sepsis and an important contributor to multi-organ failure. The proinflammatory mediators cysteinyl leukotrienes (CysLT) exert deleterious effects in the vasculature, being among the most potent vascular leakage promoting agents...
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| Format: | masterThesis |
| Language: | eng |
| Published: |
2021
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| Online Access: | https://hdl.handle.net/10216/134336 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/134336 |