Enhanced enzyme reuse through the bioconjugation of L-asparaginase and silica-based supported ionic liquid-like phase materials

L-asparaginase (ASNase) is an amidohydrolase that can be used as a biopharmaceutical, as an agent for acrylamide reduction, and as an active molecule for L-asparagine detection. However, its free form displays some limitations, such as the enzyme’s single use and low stability. Hence, immobilization...

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Bibliographic Details
Main Author: Nunes, João C. F. (author)
Other Authors: Almeida, Mafalda R. (author), Bento, Rui M. F. (author), Pereira, Matheus M. (author), Santos-Ebinuma, Valéria C. (author), Neves, Márcia C. (author), Freire, Mara G. (author), Tavares, Ana P. M. (author)
Format: article
Language:eng
Published: 2022
Subjects:
L-asparaginase
Silica-based supported ionic liquid-like phase materials
Bioconjugation
Physical adsorption
Enzyme immobilization
Molecular docking
Online Access:http://hdl.handle.net/10773/33138
Country:Portugal
Oai:oai:ria.ua.pt:10773/33138

Internet

http://hdl.handle.net/10773/33138

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