Metabolomics of Escherichia coli Treated with the Antimicrobial Carbon Monoxide-Releasing Molecule CORM-3 Reveals Tricarboxylic Acid Cycle as Major Target

In the last decade, carbon monoxide-releasing molecules (CORMs) have been shown to act against several pathogens and to be promising antimicrobials. However, the understanding of the mode of action and reactivity of these compounds on bacterial cells is still deficient. In this work, we used a metab...

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Bibliographic Details
Main Author: Carvalho, Sandra M. (author)
Other Authors: Marques, Joana (author), Romão, Carlos C. (author), Saraiva, Lígia M. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Carbon monoxide releasing molecule 3
CORM-3
E. coli
Metabolomics
Nitrogen metabolism
TCA
Pharmacology
Pharmacology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/91639
Country:Portugal
Oai:oai:run.unl.pt:10362/91639

Internet

http://hdl.handle.net/10362/91639

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