Did Germinal Centers evolve under differential effects of diversity vs affinity?

The classical view on the process of mutation and affinity maturation that occurs in GCs assumes that their major role is to generate high affinity levels of serum Abs, as well as a dominant pool of high affinity memory B cells, through a very efficient selection process. Here we present a model tha...

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Detalhes bibliográficos
Autor principal: Faro, J. (author)
Outros Autores: Combadão, J. (author), Gordo, I. (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2010
Assuntos:
Texto completo:http://hdl.handle.net/10400.7/86
País:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/86