A photoactivable amino acid based on a novel functional coumarin-6-yl-alanine

A novel fluorescent amino acid, L-4 chloromethylcoumarin-6-yl-alanine, was obtained from tyrosine by a Pechmann reaction. The assembly of the heterocyclic ring at the tyrosine side chain could be achieved before or after incorporation of tyrosine into a dipeptide, and amino acid and dipeptide ester...

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Detalhes bibliográficos
Autor principal: Fonseca, Andrea Susana Cabral da (author)
Outros Autores: Gonçalves, M. Sameiro T. (author), Costa, Susana P. G. (author)
Formato: article
Idioma:eng
Publicado em: 2012
Assuntos:
Texto completo:http://hdl.handle.net/1822/22015
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/22015