A photoactivable amino acid based on a novel functional coumarin-6-yl-alanine

A novel fluorescent amino acid, L-4 chloromethylcoumarin-6-yl-alanine, was obtained from tyrosine by a Pechmann reaction. The assembly of the heterocyclic ring at the tyrosine side chain could be achieved before or after incorporation of tyrosine into a dipeptide, and amino acid and dipeptide ester...

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Bibliographic Details
Main Author: Fonseca, Andrea Susana Cabral da (author)
Other Authors: Gonçalves, M. Sameiro T. (author), Costa, Susana P. G. (author)
Format: article
Language:eng
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1822/22015
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/22015