Correlation between octanol/water and liposome/water distribution coefficients and drug absorption of a set of pharmacologically active compounds

Absorption and consequent therapeutic action are key issues in the development of new drugs by the pharmaceutical industry. In this sense, different models can be used to simulate biological membranes to predict the absorption of a drug. This work compared the octanol/water and the liposome/water mo...

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Bibliographic Details
Main Author: Esteves, Freddy (author)
Other Authors: Moutinho, C. (author), Matos, Carla M. (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1822/27437
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/27437