Mitochondrial metabolism of 17α-hydroxyprogesterone in male sea bass (Dicentrarchus labrax): a potential target for endocrine disruptors

The metabolism of 17alpha-hydroxyprogesterone (17P(4)) was investigated in different subcellular fractions isolated from male gonads of sea bass (Dicentrarchus labrax L). The existence of CYP17 (C17,20-lyase activity) and CYP11B (11beta-hydroxylase) catalyzed reactions was demonstrated in the mitoch...

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Detalhes bibliográficos
Autor principal: Fernandes, Denise (author)
Outros Autores: Bebianno, Maria João (author), Porte, Cinta (author)
Formato: article
Idioma:eng
Publicado em: 2020
Assuntos:
17-alpha-hydroxyprogesterone
Animals
Bass
Benz(a) anthracenes
Dichlorodiphenyl dichloroethylene
Endocrine disruptors
Gas chromatography-mass spectrometry
Histocytochemistry
Male
Mitochondria
Phenols
Steroid 11-beta-hydroxylase
Steroid 17-alpha-hydroxylase
Testis
Trialkyltin compounds
Water pollutants
Chemical
Texto completo:http://hdl.handle.net/10400.1/13853
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/13853

Texto Completo

http://hdl.handle.net/10400.1/13853

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