Kinetochore-microtubule interactions "in check" by Bub1, Bub3 and BubR1: the dual task of attaching and signalling

The spindle assembly checkpoint (SAC) prevents anaphase onset until all chromosomes accomplish proper bipolar attachments to the mitotic spindle and come under tension, thereby ensuring the fidelity of chromosome segregation. Despite significant advances in our understanding of SAC signalling, a cle...

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Detalhes bibliográficos
Autor principal: Logarinho, Elsa (author)
Outros Autores: Bousbaa, Hassan (author)
Formato: article
Idioma:eng
Publicado em: 2008
Assuntos:
Animals
Cell Cycle Proteins
Humans
Kinetochores
Microtubules
Poly-ADP-Ribose Binding Proteins
Prometaphase
Protein-Serine-Threonine Kinases
Signal Transduction
Spindle Apparatus
Spindle assembly checkpoint
Kinetochore-microtubule attachments
BubR1
Bub1
Bub3
Science & Technology
Texto completo:http://hdl.handle.net/1822/61471
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/61471

Texto Completo

http://hdl.handle.net/1822/61471

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