Tetrahydropyrazolo[1,5-a]pyridine-fused steroids and their in vitro biological evaluation in prostate cancer

S.M.M.L., A.V.P. and T.M.V.D.P.eM. thank Coimbra Chemistry Centre (CQC) , supported by the Portuguese Agency for Scientific Research , “Fundação para a Ciência e a Tecnologia” ( FCT ), through project UID/QUI/00313/2019 . We also acknowledge the UC-NMR facility for obtaining the NMR data ( www.nmrcc...

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Detalhes bibliográficos
Autor principal: Jorda, Radek (author)
Outros Autores: Lopes, Susana M. M. (author), Řezníčková, Eva (author), Ajani, Haresh (author), Pereira, António V. (author), Gomes, Clara S. B. (author), Pinho e Melo, Teresa M. V. D. (author)
Formato: article
Idioma:eng
Publicado em: 2019
Assuntos:
Androgen
Galeterone
Prostate
pyrazolo[1,5-a]pyridine
Steroid
Pharmacology
Drug Discovery
Organic Chemistry
SDG 3 - Good Health and Well-being
Texto completo:https://doi.org/10.1016/j.ejmech.2019.05.064
País:Portugal
Oai:oai:run.unl.pt:10362/76917
Descrição
Resumo:S.M.M.L., A.V.P. and T.M.V.D.P.eM. thank Coimbra Chemistry Centre (CQC) , supported by the Portuguese Agency for Scientific Research , “Fundação para a Ciência e a Tecnologia” ( FCT ), through project UID/QUI/00313/2019 . We also acknowledge the UC-NMR facility for obtaining the NMR data ( www.nmrccc.uc.pt ). C.S.B.G. acknowledges the Associate Laboratory for Green Chemistry-LAQV which is financed by national funds from FCT/MCTES ( UID/QUI/50006/2019 ). The authors (RJ, EŘ) wish to acknowledge the support from the European Regional Development Fund (Project ENOCH, No. CZ.02.1.01/0.0/0.0/16_019/0000868) and Palacký University in Olomouc ( IGA_PrF_2019_013 ).

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