Mechanisms Underlying Lysosomal Dysfunction in Atherosclerotic Plaque Macrophages

Atherosclerosis is a chronic inflammatory disease mainly defined by the sequestration of lipids by macrophages in the interior of the artery wall. This pathology is the primary cause of most cardiovascular diseases (CVD). Development of atherosclerosis involves the accumulation of low-density lipopr...

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Bibliographic Details
Main Author: Ferreira, Inês Sofia da Silva (author)
Format: masterThesis
Language:eng
Published: 2022
Subjects:
Atherosclerosis
Cholesteryl hemiesters
Cholesteryl hemiazelate
Lysosomal dysfunction
Lysosomal transcription factors
Domínio/Área Científica::Engenharia e Tecnologia::Engenharia Química
Online Access:http://hdl.handle.net/10362/133432
Country:Portugal
Oai:oai:run.unl.pt:10362/133432

Internet

http://hdl.handle.net/10362/133432

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