Mechanisms Underlying Lysosomal Dysfunction in Atherosclerotic Plaque Macrophages

Atherosclerosis is a chronic inflammatory disease mainly defined by the sequestration of lipids by macrophages in the interior of the artery wall. This pathology is the primary cause of most cardiovascular diseases (CVD). Development of atherosclerosis involves the accumulation of low-density lipopr...

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Detalhes bibliográficos
Autor principal: Ferreira, Inês Sofia da Silva (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2022
Assuntos:
Atherosclerosis
Cholesteryl hemiesters
Cholesteryl hemiazelate
Lysosomal dysfunction
Lysosomal transcription factors
Domínio/Área Científica::Engenharia e Tecnologia::Engenharia Química
Texto completo:http://hdl.handle.net/10362/133432
País:Portugal
Oai:oai:run.unl.pt:10362/133432

Texto Completo

http://hdl.handle.net/10362/133432

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