Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins

During infection, plasma membrane (PM) blebs protect host cells against bacterial pore-forming toxins (PFTs), but were also proposed to promote pathogen dissemination. However, the details and impact of blebbing regulation during infection remained unclear. Here, we identify the endoplasmic reticulu...

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Detalhes bibliográficos
Autor principal: Mesquita, FS (author)
Outros Autores: Brito, C (author), Mazon, Moya MJ (author), Pinheiro, JC (author), Mostowy, S (author), Cabanes, D (author), Sousa, S (author)
Formato: article
Idioma:eng
Publicado em: 2017
Assuntos:
Actomyosin/metabolism
Animals
Bacterial Proteins/metabolism
Bacterial Toxins/metabolism
Cell Survival
Humans
Listeria monocytogenes
Membrane Glycoproteins/metabolism
Mice
Molecular Chaperones/metabolism
Pore Forming Cytotoxic Proteins/metabolism
Zebrafish
Texto completo:http://hdl.handle.net/10216/110344
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/110344

Texto Completo

http://hdl.handle.net/10216/110344

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