Development and validation of an HPLC method for the quantification of a cytotoxic dihydropyranoxanthone in biodegradable nanoparticles

Context and purpose 3,4-dihydro-12-hydroxy-2,2-dimethyl-2H(6Hi-pyrano[3,2-b]xanthen-6-one (compound 1) is a cytotoxic dihydropyranoxanthone exhibiting antiproliferative effects, inducing S-phase cell cycle arrest, and increasing the percentage of apoptotic cells in leukemia cell lines. Nevertheless,...

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Detalhes bibliográficos
Autor principal: Paiva, AM (author)
Outros Autores: Teixeira, M (author), Pereira, R (author), Barbosa, CM (author), Sousa, E (author), Pinto, MMM (author)
Formato: article
Idioma:eng
Publicado em: 2013
Texto completo:https://hdl.handle.net/10216/81197
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/81197