Farnesoid X Receptor Expression in Microscopic Colitis: A Potential Role in Disease Etiopathogenesis

Introduction: Microscopic colitis (MC) is a chronic inflammatory bowel disease with unclear etiology. Bile acid (BA) malabsorption has been described in MC patients. Farnesoid X receptor (FXR) is the main BA receptor; FXR-mediated mechanisms prevent the noxious effects of BA accumulation, preserving...

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Detalhes bibliográficos
Autor principal: Torres,Joana (author)
Outros Autores: Palmela,Carolina (author), Sena,Pedro Gomes de (author), Santos,Maria Pia Costa (author), Gouveia,Catarina (author), Oliveira,Maria Helena (author), Henriques,Ana Raquel (author), Rodrigues,Cecília (author), Cravo,Marília (author), Borralho,Paula (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Microscopic colitis
Farnesoid X receptor
Immunohistochemistry
Bile salts
Intestinal inflammation
Texto completo:http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452018000100007
País:Portugal
Oai:oai:scielo:S2341-45452018000100007

Texto Completo

http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452018000100007

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