Contact sensitizer nickel sulfate activates the transcription factors NF-kB and AP-1 and increases the expression of nitric oxide synthase in a skin dendritic cell line

Nuclear factor kappa B (NF-kB) and activating protein-1 (AP-1) transcription factors are ubiquitously expressed signaling molecules known to regulate the transcription of a large number of genes involved in immune responses, namely the inducible isoform of nitric oxide synthase (iNOS). In this study...

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Bibliographic Details
Main Author: Cruz, M. Teresa (author)
Other Authors: Gonçalo, Margarida (author), Figueiredo, Américo (author), Carvalho, Arsélio P. (author), Duarte, Carlos B. (author), Lopes, M. Celeste (author)
Format: article
Language:eng
Published: 2004
Subjects:
NO
iNOS
Skin dendritic cell
Contact sensitizer
Nickel sulfate
NF-kB
AP-1
Online Access:http://hdl.handle.net/10316/11804
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/11804

Internet

http://hdl.handle.net/10316/11804

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