Stratified 3D microtumors as organotypic testing platforms for screening pancreatic cancer therapies

Cancer-associated pancreatic stellate cells installed in periacinar/periductal regions are master players in generating the characteristic biophysical shield found in pancreatic ductal adenocarcinoma (PDAC). Recreating this unique PDAC stromal architecture and its desmoplastic microenvironment in vi...

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Detalhes bibliográficos
Autor principal: Monteiro, Maria V. (author)
Outros Autores: Gaspar, Vítor M. (author), Mendes, Luís (author), Duarte, Iola F. (author), Mano, João F. (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
Texto completo:http://hdl.handle.net/10773/34744
País:Portugal
Oai:oai:ria.ua.pt:10773/34744