Identification of yield coefficients in an E. coli model : an optimal experimental design using genetic algorithms

An optimal experimental design for yield coefficients estimation in an unstructured growth model of fed-batch fermentation of E. coli is presented. The feed profile is designed by optimisation of a scalar function based on the Fischer Information Matrix. A genetic algorithm is proposed as the optimi...

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Bibliographic Details
Main Author: Veloso, Ana C. A. (author)
Other Authors: Rocha, I. (author), Ferreira, Eugénio C. (author)
Format: conferencePaper
Language:eng
Published: 2005
Subjects:
Online Access:https://hdl.handle.net/1822/2880
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/2880