Repeated administration of a synthetic cannabinoid receptor agonist differentially affects cortical and accumbal neuronal morphology in adolescent and adult rats

Recent studies demonstrate a differential trajectory for cannabinoid receptor expression in cortical and sub-cortical brain areas across postnatal development. In the present study, we sought to investigate whether chronic systemic exposure to a synthetic cannabinoid receptor agonist causes morpholo...

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Bibliographic Details
Main Author: Carvalho, A. F. (author)
Other Authors: Reyes, B. A. S. (author), Ramalhosa, F. (author), Sousa, Nuno (author), Van Bockstaele, E. J. (author)
Format: article
Language:eng
Published: 2016
Subjects:
Age Factors
Animals
Behavior, Animal
Benzoxazines
Cannabinoid Receptor Agonists
Cell Shape
Conditioning (Psychology)
Dendritic Spines
Drug Administration Schedule
Male
Morpholines
Naphthalenes
Nucleus Accumbens
Prefrontal Cortex
Pyramidal Cells
Rats, Sprague-Dawley
Receptors, Cannabinoid
Medial prefrontal cortex
WIN 55,212-2
Golgi staining
Cannabinoid
Science & Technology
Online Access:http://hdl.handle.net/1822/61980
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/61980

Internet

http://hdl.handle.net/1822/61980

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