Genetic basis of Alzheimer's dementia: role of mtDNA mutations

Alzheimer's disease (AD) is the most common neurodegenerative disorder associated to dementia in late adulthood. Amyloid precursor protein, presenilin 1 and presenilin 2 genes have been identified as causative genes for familial AD, whereas apolipoprotein E 6034 allele has been associated to th...

ver descrição completa

Detalhes bibliográficos
Autor principal: Grazina, M. (author)
Outros Autores: Pratas, J. (author), Silva, F. (author), Oliveira, S. (author), Santana, I. (author), Oliveira, C. (author)
Formato: article
Idioma:eng
Publicado em: 2006
Texto completo:http://hdl.handle.net/10316/8413
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/8413