Insights into the spreading of ataxin-2 through extracellular vesicles

Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative polyglutamine disease caused by an aberrant expansion of the trinucleotide CAG in the coding region of the ATXN2 gene. As a result, ataxin-2, the protein product resulting from this gene, harbors an abnormally expanded polyglutamine tract,...

Full description

Bibliographic Details
Main Author: Costa, Rafael Gomes da (author)
Format: masterThesis
Language:eng
Published: 2021
Subjects:
Spinocerebellar ataxia type 2 (SCA2)
Ataxin -2
Extracellular vesicles
Exosomes
Microvesicles
Disease spreading.
Domínio/Área Científica::Ciências Médicas::Outras Ciências Médicas
Online Access:http://hdl.handle.net/10400.1/17753
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17753

Internet

http://hdl.handle.net/10400.1/17753

Similar Items