Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

With the growing body of knowledge on the contribution of efflux activity to Mycobacterium tuberculosis drug resistance, increased attention has been given to the use of efflux inhibitors as adjuvants of tuberculosis therapy. Here, we investigated how efflux activity modulates the levels of efflux b...

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Bibliographic Details
Main Author: Machado, Diana (author)
Other Authors: Perdigao, Joao (author), Portugal, Isabel (author), Pieroni, Marco (author), Silva, Pedro A. (author), Couto, Isabel (author), Viveiros, Miguel (author)
Format: article
Language:eng
Published: 2021
Subjects:
efflux inhibitors
lineages
mutations
resistance levels
tuberculosis
verapamil
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/116844
Country:Portugal
Oai:oai:run.unl.pt:10362/116844

Internet

http://hdl.handle.net/10362/116844

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