Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

With the growing body of knowledge on the contribution of efflux activity to Mycobacterium tuberculosis drug resistance, increased attention has been given to the use of efflux inhibitors as adjuvants of tuberculosis therapy. Here, we investigated how efflux activity modulates the levels of efflux b...

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Detalhes bibliográficos
Autor principal: Machado, Diana (author)
Outros Autores: Perdigao, Joao (author), Portugal, Isabel (author), Pieroni, Marco (author), Silva, Pedro A. (author), Couto, Isabel (author), Viveiros, Miguel (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
efflux inhibitors
lineages
mutations
resistance levels
tuberculosis
verapamil
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Infectious Diseases
SDG 3 - Good Health and Well-being
Texto completo:http://hdl.handle.net/10362/116844
País:Portugal
Oai:oai:run.unl.pt:10362/116844

Texto Completo

http://hdl.handle.net/10362/116844

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