Bortezomib in the treatment of refractory kidney graft rejection
Background. Bortezomib, a 26S proteasome inhibitor, is a novel treatment for refractory acute rejection. The main mechanism proposed for its action is the induction of apoptosis of mature plasma cells leading to an interruption of donor-specific antibody production, but other properties may also be...
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| Other Authors: | , , , , , , |
| Format: | other |
| Language: | eng |
| Published: |
2012
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| Subjects: | |
| Online Access: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692012000400009 |
| Country: | Portugal |
| Oai: | oai:scielo:S0872-01692012000400009 |