Disclosing the antitumour potential of the marine bromoditerpene sphaerococcenol A on distinct cancer cellular models

Nature has revealed to be a key source of innovative anticancer drugs. This study evaluated the antitumour potential of the marine bromoditerpene sphaerococcenol A on different cancer cellular models. Dose-response analyses (0.1-100 µM; 24 h) were accomplished in eight different tumour cell lines (A...

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Bibliographic Details
Main Author: Alves, Celso (author)
Other Authors: Silva, Joana (author), Afonso, Marta B (author), Guedes, Romina A. (author), Guedes, Rita C. (author), Alvariño, Rebeca (author), Pinteus, Susete (author), Gaspar, Helena (author), Goettert, Márcia I. (author), Alfonso, Amparo (author), Rodrigues, Cecília M. P. (author), Alpoím, Maria C. (author), Botana, Luis (author), Pedrosa, Rui (author)
Format: article
Language:eng
Published: 2022
Subjects:
Algae
Marine natural products
Apoptosis
Oxidative stress
Proteasome
Cancer stem cells
Caco-2 Cells
Caspase 9
Cell Line, Tumor
DNA
Diterpenes
Humans
Hydrogen Peroxide
Antineoplastic Agents
Colorectal Neoplasms
Online Access:http://hdl.handle.net/10316/100508
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/100508

Internet

http://hdl.handle.net/10316/100508

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