Disclosing the antitumour potential of the marine bromoditerpene sphaerococcenol A on distinct cancer cellular models

Nature has revealed to be a key source of innovative anticancer drugs. This study evaluated the antitumour potential of the marine bromoditerpene sphaerococcenol A on different cancer cellular models. Dose-response analyses (0.1-100 µM; 24 h) were accomplished in eight different tumour cell lines (A...

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Detalhes bibliográficos
Autor principal: Alves, Celso (author)
Outros Autores: Silva, Joana (author), Afonso, Marta B (author), Guedes, Romina A. (author), Guedes, Rita C. (author), Alvariño, Rebeca (author), Pinteus, Susete (author), Gaspar, Helena (author), Goettert, Márcia I. (author), Alfonso, Amparo (author), Rodrigues, Cecília M. P. (author), Alpoím, Maria C. (author), Botana, Luis (author), Pedrosa, Rui (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
Algae
Marine natural products
Apoptosis
Oxidative stress
Proteasome
Cancer stem cells
Caco-2 Cells
Caspase 9
Cell Line, Tumor
DNA
Diterpenes
Humans
Hydrogen Peroxide
Antineoplastic Agents
Colorectal Neoplasms
Texto completo:http://hdl.handle.net/10316/100508
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/100508

Texto Completo

http://hdl.handle.net/10316/100508

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