TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity

Growing evidences suggest that sustained neuroinflammation, caused by microglia overactivation, is implicated in the development and aggravation of several neurological and psychiatric disorders. In some pathological conditions, microglia produce increased levels of cytotoxic and inflammatory mediat...

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Bibliographic Details
Main Author: Brás, João Paulo (author)
Other Authors: Bravo, Joana (author), Freitas, Jaime (author), Barbosa, Mário Adolfo (author), Santos, Susana Gomes (author), Summavielle, Teresa (author)
Format: article
Language:eng
Published: 2022
Subjects:
Enzyme-linked immunosorbent assay (ELISA)
Mixed glial cells
Primary microglia
N9 microglial cells
TNF-alpha-induced microglia activation
miR-342
Online Access:http://hdl.handle.net/10400.22/19421
Country:Portugal
Oai:oai:recipp.ipp.pt:10400.22/19421

Internet

http://hdl.handle.net/10400.22/19421

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