Comparative genomics of wild type yeast strains unveils important genome diversity

Genome variability generates phenotypic heterogeneity and is of relevance for adaptation to environmental change, but the extent of such variability in natural populations is still poorly understood. For example, selected Saccharomyces cerevisiae strains are variable at the ploidy level, have gene a...

ver descrição completa

Detalhes bibliográficos
Autor principal: Carreto, Laura (author)
Outros Autores: Eiriz, Maria F. (author), Gomes, Ana C. (author), Pereira, Patrícia M (author), Schuller, Dorit Elisabeth (author), Santos, Manuel A. S. (author)
Formato: article
Idioma:eng
Publicado em: 2008
Assuntos:
Texto completo:http://hdl.handle.net/1822/58831
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/58831
Descrição
Resumo:Genome variability generates phenotypic heterogeneity and is of relevance for adaptation to environmental change, but the extent of such variability in natural populations is still poorly understood. For example, selected Saccharomyces cerevisiae strains are variable at the ploidy level, have gene amplifications, changes in chromosome copy number, and gross chromosomal rearrangements. This suggests that genome plasticity provides important genetic diversity upon which natural selection mechanisms can operate.