Genome-wide semi-automated annotation of transporter systems

Usually, transport reactions are added to genome-scale metabolic models (GSMMs) based on experimental data and literature. This approach does not allow associating specific genes with transport reactions, which impairs the ability of the model to predict effects of gene deletions. Novel methods for...

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Bibliographic Details
Main Author: Dias, Oscar (author)
Other Authors: Gomes, Daniel G. (author), Vilaça, P. (author), Cardoso, João (author), Rocha, Miguel (author), Ferreira, Eugénio C. (author), Rocha, Isabel (author)
Format: article
Language:eng
Published: 2017
Subjects:
Bioinformatics
Biological system modeling
Biomembranes
Databases
Genomics
Organisms
Proteins
Genome Transporters Inference
Genome-scale metabolic models
Systems Biology
TRIAGE
Transport Reactions
merlin
Science & Technology
Online Access:http://hdl.handle.net/1822/46349
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/46349

Internet

http://hdl.handle.net/1822/46349

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