Heme Cytotoxicity and the Pathogenesis of Immune-Mediated Inflammatory Diseases

Heme, iron (Fe) protoporphyrin IX, functions as a prosthetic group in a range of hemoproteins essential to support life under aerobic conditions. The Fe contained within the prosthetic heme groups of these hemoproteins can catalyze the production of reactive oxygen species. Presumably for this reaso...

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Bibliographic Details
Main Author: Larsen, Rasmus (author)
Other Authors: Gouveia, Zélia (author), Soares, Miguel P. (author), Gozzelino, Raffaella (author)
Format: article
Language:eng
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10400.7/660
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/660