Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series.

Thienopyridine skeleton has been reported as having interesting biological activity, namely antitumor [1] and antiangiogenic [2] activities. Herein we describe the synthesis of di(hetero)arylethers 1a-f and di(hetero)arylamines 2a-f functionalizing the 7-position of the thieno[3,2-b]pyridine in good...

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Bibliographic Details
Main Author: Calhelha, Ricardo C. (author)
Other Authors: Peixoto, Daniela (author), Soares, Pedro (author), Ferreira, Isabel C.F.R. (author), Abreu, Rui M.V. (author), Queiroz, Maria João R.P. (author)
Format: conferenceObject
Language:eng
Published: 2013
Online Access:http://hdl.handle.net/10198/8189
Country:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/8189