Differential roles of hydrogen peroxide and superoxide in mediating IL-1-induced NF-kappaB activation and iNOS expression in bovine articular chondrocytes

Our previous studies showed that reactive oxygen species (ROS) are required for the pro-inflammatory cytokine interleukin-1beta (IL-1) to induce the activity of the Nuclear transcription Factor-kappaB (NF-kappaB) and the expression of the inducible isoform of the nitric oxide synthase (iNOS) in bovi...

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Detalhes bibliográficos
Autor principal: Mendes, Alexandrina Ferreira (author)
Outros Autores: Caramona, M. Margarida (author), Carvalho, A. Pato (author), Lopes, M. Celeste (author)
Formato: article
Idioma:eng
Publicado em: 2003
Texto completo:http://hdl.handle.net/10316/8363
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/8363