Adaptation of asexual populations under Muller’s ratchet

We study the population genetics of adaptation in nonequilibrium haploid asexual populations. We find that the accumulation of deleterious mutations, due to the operation of Muller’s ratchet, can considerably reduce the rate of fixation of advantageous alleles. Such reduction can be approximated rea...

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Bibliographic Details
Main Author: Bachtrog, D. (author)
Other Authors: Gordo, I. (author)
Format: article
Language:eng
Published: 2010
Subjects:
Adaptation, Physiological
Evolution
Genetics, Population
Models, Biological
Background selection
Genetic hitchhiking
Muller’s ratchet
Rate of adaptation
Online Access:http://hdl.handle.net/10400.7/93
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/93

Internet

http://hdl.handle.net/10400.7/93

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