Adaptation of asexual populations under Muller’s ratchet
We study the population genetics of adaptation in nonequilibrium haploid asexual populations. We find that the accumulation of deleterious mutations, due to the operation of Muller’s ratchet, can considerably reduce the rate of fixation of advantageous alleles. Such reduction can be approximated rea...
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Formato: | article |
Idioma: | eng |
Publicado em: |
2010
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Texto completo: | http://hdl.handle.net/10400.7/93 |
País: | Portugal |
Oai: | oai:arca.igc.gulbenkian.pt:10400.7/93 |