Alginate/Chitosan Nanoparticles are Effective for Oral Insulin Delivery
Abstract Purpose To evaluate the pharmacological activity of insulin-loaded alginate/chitosan nanoparticles following oral dosage in diabetic rats. Methods Nanoparticles were prepared by ionotropic pre-gelation of an alginate core followed by chitosan polyelectrolyte complexation. In vivo activity w...
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| Other Authors: | , , , , |
| Format: | article |
| Language: | eng |
| Published: |
2007
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| Online Access: | http://hdl.handle.net/10316/7951 |
| Country: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/7951 |