T-20 and T-1249 HIV fusion inhibitors’ structure and conformation in solution: a molecular dynamics study
Fusion of the HIV envelope with the target cell membrane is a critical step of the HIV entry into the target cell. Several peptides based on the C-region of HIV gp41 have been used in clinical trials as possible HIV fusion inhibitors. Among these are T-1249 and T-20 (also known as enfurvitide). Desp...
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| Outros Autores: | , , |
| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2011
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| Assuntos: | |
| Texto completo: | http://hdl.handle.net/10174/2539 |
| País: | Portugal |
| Oai: | oai:dspace.uevora.pt:10174/2539 |