Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to Sirolimus in the rat

Side-effect minimization strategies to avoid serious side-effects of cyclosporine A (CsA), such as nephrotoxicity, have been mainly based on dose reduction and conversion to other putatively less nephrotoxic drugs, such as sirolimus (SRL), an inhibitor of the mammalian target of rapamycin. This stud...

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Detalhes bibliográficos
Autor principal: Sereno, J. (author)
Outros Autores: Vala, Helena (author), Nunes, S. (author), Rocha-Pereira, P. (author), Carvalho, E. (author), Alves, R. (author), Teixeira, F. (author), Reis, F. (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/10400.19/2746
País:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/2746